Year: 2022 | Month: December | Volume 12 | Issue 6

Ameliorative Effect of Dalbergia sissoo, Aeglemarmelos and Punica granatum on Clinical and Circulating IL-10, TNF-α, IFN-γ Status in Acute Undifferentiated Calf Diarrhoea

Himanshu Agrawal1 Manu Jaiswal1* Arvind Kumar Tripathi Ashish Srivastava Ambika Sharma P.N. Panigrahi Shubhasini Dhuriya
DOI:10.30954/2277-940X.06.2022.10

Abstract:

Neonates diarrhoea is a serious problem and considered the most common disease inducing high morbidity and mortality rates in newborn calves and responsible for severe economic losses. The present study was conducted to determine the Ameliorative effect of Dalbergia sissoo, Aeglemarmelos and Punica granatum on clinical score and circulating cytokines status in acute calf diarrhoea. The clinical scores was recorded, before and after treatment. Proinflammatory (TNF-α, IFNγ) and anti-inflammatory (IL-10) cytokines were measured in serum of calve using bovine specific quantitative ELISA Kits and revealed that significant decrease in faecal consistency score, dehydration score and depression score on day 6th (post-treatment) in all the treatment groups with highest recovery was observed in treatment group IV (T3). Significant increase in serum IL10 concentration on day 6th (post-treatment) in all the treatment groups and significant decrease in serum TNFα concentration and serum INFγ concentration on day 6th (post-treatment) in all the treatment groups with highest recovery was observed in treatment group IV (T3).

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